Utjecaj lipidnog statusa trudnica na rast i razvoj fetusa

master's thesis

• Title (english): Effect of lipide profile in healthy physiological pregnancy on fetal growth and development
• Author: Antonija Vidović
• Mentor: Matea Zajc Petranović (mentor)
• Mentor: Ana Galov (mentor)
• Committee member: Ana Galov (predsjednik povjerenstva)
• Committee member: Tomislav Ivanković (član povjerenstva)
• Committee member: Goran Kovačević (član povjerenstva)
• Committee member: Sunčica Bosak (član povjerenstva)
• Granter: University of Zagreb; Faculty of Science; (Department of Biology); Zagreb
• Defense date and country: 2017-12-14, Croatia
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Biology

Abstract

Novouspostavljena kohortna populacija srednje Dalmacije CRIBS (Kohortna studija rođenih na istočnojadranskim otocima) uključuje Split i okolicu, otoke Brač i Hvar te je osmišljena tako da omogućuje longitudinalno praćenje tijeka trudnoće, prikupljanje podataka o zdravlju majke prije i za vrijeme trudnoće, o čimbenicima okoliša koji utječu na zdravlje majke i fetusa te podatke s poroda. U ovdje prikazanu analizu bio je uključen 171 par majka-novorođenče. U odnosu na WHO (engl. World Health Organisation) i CDC/NCHS (engl. Centers for Disease Control and Prevention/National Center for Health Statistics) populacije, CRIBS novorođenčad je u prosjeku teža i veća. Pronađene su razlike u visini srednjih vrijednosti ukupnog i HDL (engl. high density lipoproteins) kolesterola u krvi trudnica ovisno o tome žive li na kopnu ili otocima; češće su povišene kod ispitanica s kopna kao i učestalost HDL kolesterola iznad referentnih vrijednosti. Majke s nižim vrijednostima HDL kolesterola od referentnih u drugom tromjesečju trudnoće, rađale su djecu statistički značajno veće porođajne duljine, a one s povišenim ukupnim i LDL (engl. low density lipoprotein) kolesterolom novorođenčad manje porođajne duljine. S obzirom na mali broj ispitanica s komplikacijama u trudnoći, nije bilo moguće utvrditi utječu li vrijednosti lipidnog profila na preeklampsiju, hipertenziju, fetalni zastoj rasta i/ili pretilost.

Abstract (english)

Cohort study CRIBS (Croatian Islands` Birth Cohort Study) includes middle Dalmatian population; city of Split and surroundings and the islands of Brač and Hvar, and was designed to enable tracking the pregnancy longitudinally; collecting data on mother's health before and during the pregnancy, data on environmental factors that can influence mother's and fetal health, and birth data. Analysis included 171 mother-newborn pairs. In relation to WHO (World Health Organisation) and CDC/NCHS (Centers for Disease Control and Prevention/National Center for Health Statistics) referent populations, CRIBS newborns were on average heavier and longer. Differences in mean levels of total and HDL (high density lipoprotein) cholesterol were found depending on whether the mothers were living on the mainland or on the islands; higher level were found in mainland's mothers as well as the higher prevalence of elevated HDL. Pregnant women with lower mean HDL cholesterol in their second trimester gave birth to longer newborns, while those with normal or elevated LDL (low density lipoprotein) had newborns of smaller lenght. Considering small number of participants with pregnancy complications, it was not possible to determine whether lipid profile values associated with preeclampsia, hypertension, fetal growth retardation and/or obesity.

• Keywords: trudnoća; fetus; novorođenče; dislipidemija; antropometrija; CRIBS studija
• Keywords (english): pregnancy; fetus; newborn; dyslipidemia; anthropometry; CRIBS study
• Language: croatian
• URN:NBN: urn:nbn:hr:217:655448
• Study programme: Title: Experimental Biology; Study programme type: university; Study level: graduate; Academic / professional title: magistar/magistra eksperimentalne biologije (magistar/magistra eksperimentalne biologije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access; Embargo expiration date: 2018-12-14
• Created on: 2018-01-31 10:13:37