Morfometrijska analiza promjera jezgara Leydigovih stanica i sjemenskih kanalića kod kriptorhičnih testisa u mladih muškaraca

master's thesis

• Title (english): Morfometrical analysis of diameters of leydig cells nuclei and seminiferous tubules at cryptorchid testes of young males
• Author: Anamarija Jagić
• Mentor: Ljerka Banek (mentor)
• Committee member: Ljerka Banek (predsjednik povjerenstva)
• Committee member: Gordana Lacković-Venturin (član povjerenstva)
• Committee member: Ines Radanović (član povjerenstva)
• Committee member: Draginja Mrvoš-Sermek (član povjerenstva)
• Committee member: Mirjana Kalafatić (član povjerenstva)
• Granter: University of Zagreb; Faculty of Science; (Department of Biology); Zagreb
• Defense date and country: 2009, Croatia
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Biology

Abstract

Leydigove stanice smještene su u intersticijskom tkivu testisa između sjemenskih kanalića. Istraživanje je obuhvatilo biopsije kriptorhičnih testisa petnaestorice muškaraca (18 do 27 god). Kao kontrola poslužili su uzorci tkiva testisa dvojice muškaraca (28 i 29 god) dobivenih obdukcijom nakon prometne nesreće. Cilj rada bio je istražiti da li se u biopsijama kriptorhičnih testisa mladih muškaraca mijenjaju promjeri jezgara Leydigovih stanica te sjemenskih kanalića u odnosu na kontrolnu skupinu. Načinjena je kvantitativna analiza primjenom morfometrije koja je uključivala usporedbu kontrolnih uzoraka i uzoraka sjemenika kriptorhičnih muškaraca s obzirom na promjere sjemenskih kanalića te jezgre Leydigovih stanica uz sjemenske kanaliće i krvne kapilare. Rezultati istraživanja pokazuju značajno smanjenje promjera jezgara Leydigovih stanica uz sjemenske kanaliće kao i uz krvne žile kod kriptorhičnih testisa u odnosu na kontrolnu skupinu (P < 0.01). Također, promjer sjemenskih kanalića bio je značajno smanjen kod kriptorhičnih testisa u odnosu na kontrolu (P < 0.01).

Abstract (english)

Leydig cells are placed inside the interstitium tissue between seminiferous tubules. The research included biopsies of cryptorchid testes of 15 men (aged 18 - 27). As controls, samples of biopsies of two patients (aged 28 and 29) who had a car accident, were used. The aim of this thesis was to investigate possible changes in diameters of Leydig cells nuclei and seminiferous tubules according to controls. A quantitative analysis was done by methods of morfometry and included comparison of the control samples and samples of testicles of infertile men in connection with the diameters of seminiferous tubules and and of Leydig cells nuclei beside seminiferous tubules and blood vessels. The results of this research show lower values for diameter of Leydig cells nuclei by seminiferous tubules and also along with blood vessels at cryptorchid testes according to controls (P < 0.01). Also, diameter of seminiferous tubules was significantly lower at cryptorchid testes related to controls (P < 0.01).

• Keywords: jezgre Leydigovih stanica; sjemenski kanalići; kriptorhizam; morfometrija
• Keywords (english): nuclei of Leydig cells; seminiferous tubules; cryptorchidism; morfometry
• Language: croatian
• URN:NBN: urn:nbn:hr:217:621493
• Study programme: Title: Integrated undergraduate and graduate university study of Biology and Chemistry Education; specializations in: Integrated undergraduate and graduate university study of Biology and Chemistry Education; Course: Integrated undergraduate and graduate university study of Biology and Chemistry Education; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: magistar/magistra edukacije biologije i kemije (magistar/magistra edukacije biologije i kemije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2018-03-12 09:46:33