Flavonoidi propolisa i biljaka u kontroli alergije i upale

undergraduate thesis

• Title (english): Flavonoids from propolis and plants in control of allergy and inflammation
• Author: Ivana Škrnjug
• Mentor: Nada Oršolić (mentor)
• Granter: University of Zagreb; Faculty of Science; (Department of Biology); Zagreb
• Defense date and country: 2009, Croatia
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Biology

Abstract

Flavonoidi čine heterogenu skupinu prirodnih polifenolnih spojeva koje sintetiziraju biljni organizmi, a zastupljeni su u svakodnevnoj prehrani ljudske populacije. Eksperimentalno je zabilježena aktivnost flavonoida na biološke sustave u smislu modulacije imunoloških i antioksidacijskih procesa. Nalazimo ih u voću, povrću i popularnim pićima poput vina, piva i čajeva. Neke biljke posjeduju ljekovita svojstva upravo zbog visokog udjela flavonoida u svojim iscrpinama. Propolis («pčelinje ljepilo») sadrži velike količine flavonoida, a već je od davnina poznat kao ljekoviti pripravak u «narodnoj medicini». U ovom seminarskom radu dan je pregled kemijskih svojstava flavonoida u smislu njihova utjecaja na imunološke procese kao što su alergijske i upalne reakcije. Osim pozitivnih farmakoloških svojstava, dan je i osvrt na zabilježene slučajeve pojave alergijskih reakcija kod pacijenata podvrgnutih medicinskoj terapiji čiji se sastav bazirao na propolisu. Suvremena istraživanja su usmjerena na pronalazak novih lijekova, a eksperimentalno dokazana farmakološka svojstva flavonoida ukazuju na njihov velik potencijal za razvitak medicinskih terapija u budućnosti.

Abstract (english)

The flavonoids are heterogenous group of ubiquitous plant polyphenols that aboundant in human diet and are endowed with several biological activities, including immunomodulating and antioxidant activities. They are much abundant in fruit, vegetables and popular drinks, such as wine, beer and tea. Some plants exhibit therapeutic effects particulary because their extracts contain large amount of flavonoids. Propolis, also called «bee glue», is well known in traditional medicine and it also abounds with flavonoids. Intention of this review is to point out chemical properties and therapeutic effects of propolis and related flavonoids on allergy and allergic inflammatory deseases. Besides positive pharmacological properties, here are reviewed some cases of allergic reactions to propolis, within medical therapies applied to patients. Modern biomedical researches are focused on new medical therapies development. Experimentally approved pharmacological properties of flavonoids demonstrate their potential for developent of new medical therapies in the future.

• Keywords: flavonoidi; propolis
• Keywords (english): flavonoids; propolis
• Language: croatian
• URN:NBN: urn:nbn:hr:217:294761
• Study programme: Title: Molecular Biology; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2018-03-21 10:10:36