Stvaranje umjetnog života u laboratoriju

undergraduate thesis

• Title (english): Creation of synthetic life in laboratory
• Author: Ivana Majstorović
• Mentor: Mirjana Kalafatić (mentor)
• Granter: University of Zagreb; Faculty of Science; (Department of Biology); Zagreb
• Defense date and country: 2010, Croatia
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Biology

Abstract

Ljudi su oduvijek bili fascinirani životom i pokušali su ga stvoriti više nego jednom kroz povijest. Pojavom novog područja biologije, sintetske biologije, koje kombinira znanost i inženjerstvo; je to postalo moguće. Ovaj rad daje kratki pregled događaja koji su doveli znanstvenike iz J. Craig Venter Instita (JCVI) do objave rezultate u kojima opisuju uspješno konstruiranje prve samoreplicirajuće sintetske bakterijske stanice. Tim znanstvenika je sintetizirao modificirani kromosom iz genoma bakterije Mycoplasma mycoides veličine 1.08 milijuna parova baza. Sintetska stanica je nazvana Mycoplasma mycoides JCVI-syn1.0 i dokaz je da genomi mogu biti dizajnirani u računalu, kemijski stvoreni u laboratoriju te transplantirani u domaćinsku stanicu gdje će stvoriti novu samoreplicirajuću stanicu kontroliranu samo sintetičkim genomom.

Abstract (english)

People have always been fascinated by life and have tried to create it more than once throughout the history. With the appearance of new area of biology, the synthetic biology, which combines science and engineering; that become possible. This work gives a short review of events that led to publishing results of scientists at the J. Craig Venter Institute (JCVI) describing the successful construction of the first self-replicating, synthetic bacterial cell. The team of scientists synthesized the 1.08 million base pair chromosome of a modified Mycoplasma mycoides genome. The synthetic cell is called Mycoplasma mycoides JCVIsyn1.0 and is the proof of principle that genomes can be designed in the computer, chemically made in the laboratory and transplanted into a recipient cell to produce a new self-replicating cell controlled only by the synthetic genome.

• Keywords: umjetna stanica; umjetni život
• Keywords (english): artificial cell; synthetic life
• Language: croatian
• URN:NBN: urn:nbn:hr:217:640591
• Study programme: Title: Ecology; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2018-03-28 08:56:41