Min-protein oscillations in Escherichia coli with spontaneous formation of two-stranded filaments in a three-dimensional stochastic reaction-diffusion model

Scientific paper - Original scientific paper

• Author: Nenad Pavin
• Author: Hana Čipčić Paljetak
• Author: Vladimir Krstić
• Author's institution: University of Zagreb; Faculty of Science; (Department of Physics)
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Physics
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Biology

Abstract (english)

We introduce a three-dimensional stochastic reaction-diffusion model to describe MinD/MinE dynamical structures in Escherichia coli. This model spontaneously generates pole-to-pole oscillations of the membrane-associated MinD proteins, MinE ring, as well as filaments of the membrane-associated MinD proteins. Experimental data suggest MinD filaments are two-stranded. In order to model them we assume that each membrane-associated MinD protein can form up to three bonds with adjacent membrane-associated MinD molecules and that MinE induced hydrolysis strongly depends on the number of bonds MinD has established.

• Keywords (english): MinD, MinE, cell division, pole-to-pole oscillations, E. coli, reaction-diffusion model
• Language: english
• Publication type: Scientific paper - Original scientific paper
• Publication status: Published
• Peer review: Peer review - international
• Publication version: Published version
• Journal title: Physical Review E
• Numbering: vol. 73, no. 2, 021904
• p-ISSN: 1539-3755
• DOI: https://doi.org/10.1103/PhysRevE.73.021904
• URN:NBN: urn:nbn:hr:217:628074
• Publication: 2006
• Document URL: http://link.aps.org/doi/10.1103/PhysRevE.73.021904
• Type of resource: Text
• Access conditions: Open access
• Public note: Copyright (2006) by the American Physical Society.
• Created on: 2019-10-15 18:05:58