Primjena nanomaterijala u regenerativnoj medicini

undergraduate thesis

• Title (english): Application of nanomaterials in regenerative medicine
• Author: Tea Sonicki
• Mentor: Petra Peharec Štefanić (mentor)
• Granter: University of Zagreb; Faculty of Science; (Department of Biology); Zagreb
• Defense date and country: 2020-07-24, Croatia
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Biology

Abstract

Nanomaterijali su otvorili brojne mogućnosti u regenerativnoj medicini srčanog mišića
nakon infarkta te kože u slučaju dijabetičkog stopala te nakon opeklina. Kod regeneracije
srčanog mišića nanomaterijali s magnetskim svojstvima su omogućili manipulaciju
korištenjem vanjske magnetne sile. Proučavanjem raznih nanomaterijala pokazano je da se
njihovim korištenjem povećava vodljivost zbog stvaranja većeg broja pukotinskih spojišta,
smanjivanja praga koji je nužan za postizanje kontrakcije, smanjenja osjetljivosti na
oksidativni stres, povećanja angiogeneze i dužeg zadržavanja tkivno specifičnih lijekova. Za
regeneraciju kože postoje već komercijalno dostupni lijekovi bazirani na nanomaterijalima
koji omogućuju brže zacjeljivanje rane, smanjenje upale i brže angiogeneze.

Abstract (english)

Nanomaterials have opened up numerous possibilities in the regenerative medicine of the
heart muscle after a heart attack and skin in the case of diabetic foot and after burns. In the
regeneration of the heart muscle, nanomaterials with magnetic properties enabled
manipulation using an external magnetic force. Studies of various nanomaterials have shown
that their use increases conductivity due to the formation of more crack junctions, lowering
the threshold required to achieve contraction, reducing sensitivity to oxidative stress,
increasing angiogenesis and longer retention of tissue-specific drugs. For skin regeneration,
there are already commercially available drugs based on nanomaterials that allow faster
wound healing, reduced inflammation and faster angiogenesis.

• Keywords: Nanomaterijali
• Language: croatian
• URN:NBN: urn:nbn:hr:217:757891
• Study programme: Title: Molecular Biology; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2020-07-24 11:28:30