Utjecaj kristalizacijskih uvjeta na pojavnost kokristala uree i kompleksa bis(L-prolinato)bakra(II)

master's thesis

• Title (english): The influence of crystallization conditions on the occurrence of urea cocrystals with bis(L-prolinato)copper (II) complex
• Author: Marija Leko
• Mentor: Ivica Đilović (mentor)
• Committee member: Ivica Đilović (predsjednik povjerenstva)
• Committee member: Đani Škalamera (član povjerenstva)
• Committee member: Jana Pisk (član povjerenstva)
• Committee member: Adriana Kenđel (član povjerenstva)
• Granter: University of Zagreb; Faculty of Science; (Department of Chemistry); Zagreb
• Defense date and country: 2021-07-16, Croatia
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Chemistry

Abstract

U sklopu ovog rada priređeni su kompleksni spojevi bakra(II) i L-prolina mehanokemijskom
sintezom postupkom finog mljevenja. Dobiveni trans-bis(L-prolinato)bakar(II) kompleksi
korišteni su za dobivanje kookristala s ureom. U tim su slučajevima kokristali nastali iz
otopina različitih sastava. Vezanjem uree preferentno nastaje cis-izomer te je ispitana
mogućnost izolacije čistog izomera reakcijama u čvrstom stanju. Svi dobiveni produkti
okarakterizirani su infracrvenom spektroskopijom, difrakcijom rendgenskog zračenja na
jediničnom kristalu ili praškastom uzorku i termogravimetrijskim metodama analize.
Određena je molekulska i kristalna struktura kokristala uree i kompleksa bis(Lprolinato)
bakra(II). Utvrđena je oktaedarska koordinacija metalnog iona Cu(II) uz
deformaciju geometrije, gdje su u aksijalnim položajima vezane molekula vode i molekula
prolina susjedne molekule spoja. Analiza je potvrdila nastajanje cis-izomera vezanjem uree i
karboksilatne skupine prolina vodikovim vezama. Reakcijama u čvrstom stanju nije uspješno
izoliran cis-bis(L-prolinato)bakar(II) kompleks.

Abstract (english)

This diploma thesis presents synthesis of complexes of copper(II) with L-proline via neat
mechanochemical synthesis. Obtained trans-bis(L-prolinato)copper(II) complexes were used
for the synthesis of cocrystals with urea and water. In these cases, cocrystals were prepared
from solutions with different compositions. Urea binding preferably formed cis-isomer and
the possibility of isolating pure isomer by solid state reactions was investigated. All obtained
products were characterized by infrared spectroscopy, single and powder X-ray diffraction
analysis and thermogravimetric methods.
The molecular and crystal structure of urea cocrystals with bis(L-prolinato)copper(II) complex
were determined. It was found that Cu(II) ions exhibit distorted octahedral coordination
geometry, where axial positions are occupied by water molecules and oxygen atoms of the
adjacent proline molecule. The analysis confirmed the formation of cis-isomer by hydrogen
bond formation between the urea and the carboxylate group of proline. The cis-bis(Lprolinato)
copper(II) complex was not successfully isolated by solid state reactions.

• Keywords: bakar(II); L-prolin; urea; kristalizacija; cis-trans izomerizacija; kristalno inženjerstvo; međumolekulske interakcije
• Keywords (english): copper(II); L-proline; urea; crystallization; cis-trans isomerization; crystal engineering; intermolecular interactions
• Language: croatian
• URN:NBN: urn:nbn:hr:217:940709
• Study programme: Title: Graduate university studies in chemistry; specializations in: Research programme; Course: Research programme; Study programme type: university; Study level: graduate; Academic / professional title: magistar/magistra kemije (magistar/magistra kemije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access; Embargo expiration date: 2023-07-16
• Created on: 2021-08-27 09:50:04