Međustanična komunikacija u ranom razvoju kralježnjaka

undergraduate thesis

• Title (english): Cell-cell communication in early stages of vertebrate development
• Author: Lorena Beretin
• Mentor: Romana Gračan (mentor)
• Granter: University of Zagreb; Faculty of Science; (Department of Biology); Zagreb
• Defense date and country: 2021-09-24, Croatia
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Biology

Abstract

Potkoljeno kralježnjaka broji preko 70 000 različitih vrsta. Svaka jedinka unutar ovog
potkoljena nastaje iz jedne oplođene stanice, zigote, spajanjem spermija i jajne stanice. Iz
zigote se uzastopnim dijeljenjem i složenim procesima razvija cijeli organizam, složeni sustav
koji radi prema evolucijski naslijeđenim mehanizmima, ali je ujedno i unikatan i jedinstven za
svaku jedinku. Za formiranje embrija iz zigote potrebne su pravilne diobe stanica i povećanje
njihovog broja, stvaranje asimetrija i određivanje strana tijela, diferencijacija stanica i složeniji
procesi koji je slijede, a to su morfogeneza i organogeneza. Tijekom ranog razvoja kralježnjaka
diferencijacija stanica potaknuta je induktivnim signalima iz okoliša u kojemu se ta stanica
nalazi. Proces indukcije temelji se na izmjeni signala između stanica. Putem signalnih molekula
u koje ubrajamo parakrine i jukstakrine faktore stanice komuniciraju te se međusobno
usmjeravaju ka pravilnom razvojnom putu. Cilj ovog rada bio je predstaviti osnovne signalne
puteve tijekom ranog razvoja kralježnjaka.

Abstract (english)

The vertebrate subphylum counts over 70,000 different species. Each individual within
this subphylum is formed from a single fertilised cell called the zygote, by merging a sperm
and ovum cell. From a zygote stadium, through successive divisions and complex processes,
an entire organism develops as a complex system that works according to evolutionarily
inherited mechanisms but is also unique to each individual. The formation of embryos from
zygotes requires proper cell division and increase in their number, creation of asymmetry and
determination of body axis, cell differentiation, and more complex processes that follow,
morphogenesis and organogenesis. During early vertebrate development, cell differentiation is
stimulated by inductive signals from the environment in which that cell is located. The
induction process is based on the exchange of signals among cells. Through signalling
molecules, which include paracrine and juxtacrine factors, cells communicate and direct each
other towards the correct developmental path. The aim of this paper was to present the basic
signalling pathways during early vertebrate development

• Keywords: kralježnjaci; oplodnja; razvoj; signalizacija
• Keywords (english): vertebrates; fertilisation; development; signalling
• Language: croatian
• URN:NBN: urn:nbn:hr:217:586142
• Study programme: Title: Ecology; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2021-09-27 12:56:29