Uspostava zigotne kontrole razvoja u viših biljaka

undergraduate thesis

• Title (english): Maternal-to-zygotic transition in higher plants
• Author: Karla Tolić
• Mentor: Dunja Leljak-Levanić (mentor)
• Granter: University of Zagreb; Faculty of Science; (Department of Biology); Zagreb
• Defense date and country: 2024-09-19, Croatia
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Biology

Abstract

Životni ciklus biljaka i životinja započinje oplodnjom jajne stanice kojom nastaje zigota. Kratko nakon oplodnje razvoj embrija temelji se na transkriptima naslijeđenim od jajne stanice. Postepeno kontrolu razvoja preuzima zigota/embrij tijekom tranzicijskog procesa (MZT). Uspostava zigotne/embrijske kontrole razvoja odvija se postepeno kroz razgradnju naslijeđenih majčinskih transkripata te aktivaciju zigotnog genoma (ZGA). Kod biljaka, za razliku od životinja, aktivacija zigotnog genoma započinje u stadiju zigote te rezultira prvom staničnom diobom. Geni koji se eksprimiraju u ranim stadijima razvoja biljaka uključeni su u uspostavu polarnosti zigote te apikalno-bazalne osi koja je temelj za nastavak embriogeneze. Mehanizmi degradacije naslijeđenih transkripata kod biljaka još nisu poznati. Dosadašnja istraživanja upućuju na postojanje razlika u procesu uspostave zigotne kontrole razvoja između jedosupnica i dvosupnica. Najnovija istraživanja provedena na životinjskim modelima ukazala su na važnost alternativnog prekrajanja u procesu MZT, međutim ovakva istraživanja tek je potrebno provesti na biljnim modelima. Perspektivu za proučavanje alternativnog prekrajanja u okviru uspostave zigotne kontrole razvoja kod uročnjaka predstavlja proteinska porodica MATH-BTB.

Abstract (english)

The life cycle of plants i animals begins with the fertilization of the egg cell, which results in the formation of a zygote. Shortly after fertilization, the development of the embryo relies on transcripts inherited from the egg cell. Gradually, the zygote/embryo takes control of development during the maternal-to-zygotic transition (MZT). Maternal-to-zygotic transition occurs progressively through the degradation of inherited maternal transcripts and the activation of the zygotic genome (ZGA). Unlike animals, in plants zygotic genome activation begins at the zygote stage and it leads to the first cell division. Genes expressed during the early stages of plant development are involved in establishing the polarity of the zygote and the apical-basal axis, which is essential for further embryogenesis. The mechanisms which govern degradation of inherited transcripts in plants are still unknown. Previous studies suggest differences in the process of maternal-to-zygotic transition between monocots and dicots. Recent research on animal models has highlighted the importance of alternative splicing in the MZT process, but such studies are yet to be conducted on plant models. The MATH-BTB protein family presents perspective for studying alternative splicing in the context of MZT process in Arabidopsis.

• Keywords: aktivacija zigotnog genoma (ZGA); alternativno prekrajanje; MATH-BTB proteini; embrionalni razvoj biljaka
• Keywords (english): zygotic genome activation (ZGA); alternative splicing; MATH-BTB proteins; plant embrio development
• Language: croatian
• URN:NBN: urn:nbn:hr:217:906848
• Study programme: Title: Molecular biology-University undergraduate programme; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-10-03 09:28:03