Utjecaj reakcijskih uvjeta na ishod kondenzacije 2-hidroksi-1-naftaldehida i 4-aminopiridina

master's thesis

• Title (english): The influence of reaction conditions on the outcome of 2-hydroxy-1-naphthaldehyde condensation with 4-aminopyridine
• Author: Martina Ivković
• Mentor: Dominik Cinčić (mentor)
• Committee member: Dominik Cinčić (predsjednik povjerenstva)
• Committee member: Ines Primožič (član povjerenstva)
• Committee member: Iva Juranović Cindrić (član povjerenstva)
• Committee member: Vladimir Stilinović (član povjerenstva)
• Granter: University of Zagreb; Faculty of Science; (Department of Chemistry); Zagreb
• Defense date and country: 2018-02-14, Croatia
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Chemistry

Abstract

U sklopu ovog diplomskog rada izučavana je mogućnost kondenzacije 4-aminopiridina i 2-hidroksi-1-naftaldehida metodama mehanokemijske sinteze i sinteze u otopini, kao poznatim načinima dobivanja imina, te metodom ubrzanog starenja. Promjenom množinskog omjera reaktanata, vrste otapala i vremena trajanja reakcije pokušalo se doći do spoznaja o reaktivnosti prekursora te utjecaju različitih reakcijskih uvjeta na ishod sinteze. Pripravljena su dva jedinična kristala metodama sinteze u otopini, jedan derivat 1,2-naftokinona te kokristal imina i 2-hidroksi-1-naftaldehida.
Dobiveni produkti izučavani su metodom difrakcije rentgenskih zraka na praškastom uzorku, FTIR spektroskopijom, termogravimetrijom i razlikovno-pretražnom kalorimetrijom. Za oba pripravljena kristala metodom difrakcije rentgenskog zračenja na jediničnom kristalu iznađena je molekulska i kristalna struktura.

Abstract (english)

Within this diploma thesis, a possibility of 2-hydroxy-1-naphthaldehyde condensation with 4-aminopyridine was studied by mechanochemical and traditional solution synthesis methods, which are traditional methods for obtaining imines, as well as by the accelerated aging method. The goal was to attain further insights into precursor reactivity and the effect of various reaction conditions on the outcome of synthesis by changing the molar ratio of reactants, solvent types and reaction time. Two single-crystals were obtained by solution synthesis, 4-ethoxy-1,2-naphthoquinone and a cocrystal of imine and 2-hydroxy-1-naphthaldehyde.
Synthesized compounds were described by powder X-ray diffraction, FTIR spectroscopy thermogravimetry and differential scanning calorimetry. The crystal and molecular structures of the two prepared compounds were determined by single-crystal X-ray diffraction.

• Keywords: imini; kokristali; mehanokemijska sinteza; sinteza u otopini
• Keywords (english): imines; cocrystals; mechanochemical synthesis; solution synthesis
• Language: croatian
• URN:NBN: urn:nbn:hr:217:669202
• Study programme: Title: Graduate university studies in chemistry; specializations in: Research programme; Course: Research programme; Study programme type: university; Study level: graduate; Academic / professional title: magistar/magistra kemije (magistar/magistra kemije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access; Embargo expiration date: 2020-02-14
• Created on: 2018-02-21 14:38:57