Makrofagni centri kao histokemijski pokazatelji stresa

undergraduate thesis

• Title (english): Macrophage centers as histochemical indicators of stress
• Author: Lucija Kovačević
• Mentor: Gordana Lacković-Venturin (mentor)
• Granter: University of Zagreb; Faculty of Science; (Department of Biology); Zagreb
• Defense date and country: 2010, Croatia
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Biology

Abstract

Makrofagni centri, također poznati i kao melano makrofagni centri, su nakupine karakterističnih pigmentiranih stanica unutar tkiva heterotermnih kralježnjaka. U riba se obično nalaze u stromi hemopoetskog tkiva slezene, jetre i bubrega gdje se pomoću različitih histokemijskih metoda proučava njihov izgled i sastav. Makrofagni centri obično sadrže različite pigmente uključujući i melanin. Broj različitih pigmenata i njihov volumen povećavaju se u starijih jedinki ili u prisutnosti različitih bolesti. Nedavna istraživanja sugeriraju da su to prvenstveno mjesta primarne malenogeneze nego li samo pohrane melanina. Makrofagni centri povećavaju frekvenciju i veličinu u uvjetima okolišnog stresa te time ukazuju na zdravstveno stanje jedinke i predloženi su kao pouzdani biomarkeri za kvalitetu vode.

Abstract (english)

Macrophage centers, also known as Melano-macrophage centres, are distinctive groupings of pigment-containing cells within the tissues of heterothermic vertebrates. In fish they are normally located in the stroma of the haemopoietic tissue of the spleen and the kidney and are studied using variety of histochemical methods. Melano-macrophage centres usually contain a variety of pigments, including melanins, and these increase in range and volume in older fish or in the presence of different diseases. Recent work suggests that they are a site of primary melanogenesis rather than mere storage. Melano-macrophage centres increase in size or frequency in conditions of environmental stress and have been suggested as reliable biomarkers for water quality.

• Keywords: makrofagni centri
• Keywords (english): macrophage centers
• Language: croatian
• URN:NBN: urn:nbn:hr:217:051095
• Study programme: Title: Molecular Biology; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2018-03-27 09:39:40