Psihoneuroimunologija depresivnog poremećaja: mehanizmi i kliničke implikacije

undergraduate thesis

• Title (english): Psychoneuroimmunology of depressive disorder: mechanisms and clinical implications
• Author: Saša Petrović
• Mentor: Julija Erhardt (mentor)
• Granter: University of Zagreb; Faculty of Science; (Department of Biology); Zagreb
• Defense date and country: 2010, Croatia
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Biology

Abstract

Depresija je ozbiljna bolest od koje svakim danom oboljeva sve više ljudi. Osim utjecaja na imunološki sustav, depresija pridonosi i patofiziologiji bolesti. Antidepresivi djeluju pretežno na razini reapsorpcije neurotransmitera, no utječu i na stanice imunološkog sustava, što je potrebno još detaljnije istražiti. Mozak prepoznaje citokine kao signal infekcije ili ozljede bolesti te odgovara prikladnom reakcijom, no u slučaju neravnoteže neuroendokrinog i imunološkog sustava može doći do indukcije promjena u ponašanju te razvoja depresije.

Abstract (english)

Depression is a serious disease which takes toll on more people every day. Besides the impact on the immune system, depression contributes to the pathophysiology of the disease. Antidepressants act primarily on the level of the uptake of the neurotransmitter, but also affect the cells of the immune system, what needs more detailed research. The brain recognizes cytokines as a sign of the infection or injury, and it reacts appropriately to that, but in case of imbalance of the neuroendocrine and immune system it may induce changes in behavior and the development of depression.

• Keywords: depresija
• Keywords (english): depression
• Language: croatian
• URN:NBN: urn:nbn:hr:217:618479
• Study programme: Title: Molecular Biology; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2018-03-29 07:46:19