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undergraduate thesis
Proizvodnja monoklonalnih protutijela u biljkama
2012. urn:nbn:hr:217:206947
Faraho, Ivan
University of Zagreb
Faculty of Science
Department of Biology

Cite this document

Faraho, I. (2012). Proizvodnja monoklonalnih protutijela u biljkama (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:206947

Faraho, Ivan. "Proizvodnja monoklonalnih protutijela u biljkama." Undergraduate thesis, University of Zagreb, Faculty of Science, 2012. https://urn.nsk.hr/urn:nbn:hr:217:206947

Faraho, Ivan. "Proizvodnja monoklonalnih protutijela u biljkama." Undergraduate thesis, University of Zagreb, Faculty of Science, 2012. https://urn.nsk.hr/urn:nbn:hr:217:206947

Faraho, I. (2012). 'Proizvodnja monoklonalnih protutijela u biljkama', Undergraduate thesis, University of Zagreb, Faculty of Science, accessed 19 April 2024, https://urn.nsk.hr/urn:nbn:hr:217:206947

Faraho I. Proizvodnja monoklonalnih protutijela u biljkama [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Science; 2012 [cited 2024 April 19] Available at: https://urn.nsk.hr/urn:nbn:hr:217:206947

I. Faraho, "Proizvodnja monoklonalnih protutijela u biljkama", Undergraduate thesis, University of Zagreb, Faculty of Science, Zagreb, 2012. Available at: https://urn.nsk.hr/urn:nbn:hr:217:206947

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Metadata
TitleProizvodnja monoklonalnih protutijela u biljkama
Title (english)Production of monoclonal antibodies in plants
AuthorIvan Faraho
MentorBiljana Balen (mentor)
GranterUniversity of Zagreb
Faculty of Science
(Department of Biology)
Zagreb
Defense date and country2012, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Monoklonalna protutijela su protutijela izolirana iz samo jednog tipa stanica. Do nedavno su se izolirala samo iz animalnih stanica, no uočeno je da se kao izvor rekombinantnih protutijela mogu koristiti i biljke, no potrebno im je izmijeniti glikozilacijski put na način da se prilagodi onome u animalnim stanicama. Usporedbom proizvodnje protutijela u biljnim i animalnim stanicama znanstvenici su došli do zaključka da protutijela proizvedena u biljkama pokazuju pravilnu strukturu, te čak i bolju sposobnost vezanja antigena. Također, biljke su prepoznate i kao ekonomičniji izvor rekombinantnih protutijela, uzevši u obzir brzinu i cijenu proizvodnje.
Abstract (english)
Monoclonal antibodies are antibodies which can be isolated from one cell type. Until recently they were isolated only from animal cell cultures, but it has been discovered that plants as well can be used as a source of recombinant antibodies, but it is necessary to change glycosylation patterns in order to be mammalian-like. Comparing plant- and animal-derived antibodies scientists have concluded that antibodies produced in plants show right structure, and have even better antigen-binding specificity. Furthermore, plants have been recognized as a more economical source of recombinant antibodies, considering speed and cost of production.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:206947
Study programmeTitle: Molecular Biology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2018-04-16 09:13:13