Analiza ishoda liječenja pacijenata s Clostridium difficile infekcijom logističkom regresijom

master's thesis

• Author: Matea Bogdanić
• Mentor: Anamarija Jazbec (mentor)
• Committee member: Anamarija Jazbec (predsjednik povjerenstva)
• Committee member: Eduard Marušić-Paloka (član povjerenstva)
• Committee member: Marko Erceg (član povjerenstva)
• Committee member: Goran Radunović (član povjerenstva)
• Granter: University of Zagreb; Faculty of Science; (Department of Mathematics); Zagreb
• Defense date and country: 2019-03-01, Croatia
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Mathematics

Abstract

U ovom radu analizirali smo ishode liječenja pacijenata s Clostridium difficile infekcijom. Korištena je metoda logističke regresije na bazi podataka koja se sastoji od 1080 observacija i 13 varijabli. Istraživanje je odobreno od strane Etičkog povjerenstva Klinike za infektivne bolesti „Dr. Fran Mihaljević“. Sve potrebne varijable prikupili su Nikolina Bogdanić, dr.med., Karlo Vidović, dr.med. te doc. dr. sc. Mirjana Balen Topić, specijalist infektolog, iz originalne arhivirane medicinske dokumentacije. Za obradu podataka je korišten statistički program SAS. Iz provedene analize smo zaključili da su varijable koje imaju značajan utjecaj na krajnji ishod liječenja na razini značajnosti od 5% McCabe score, klinička težina bolesti, pokretnost i konkomitantne infekcije.

Abstract (english)

In this paper we have analyzed the outcomes of treatment of patients with Clostridium difficile infection. A logistic regression method was used on a database consisting of 1080 observations and 13 variables. The study was approved by the Ethics Committee of the Clinic for Infectious Diseases ”Dr. Fran Mihaljević ”. All necessary variables were collected by Nikolina Bogdanić, MD, Karlo Vidović, MD. and doc. dr. sc. Mirjana Balen Topić, an infectious diseases specialist, from the original archived medical documentation. The statistical program SAS was used for data processing. Analysis showed that the variables that significantly affect the ultimate outcome of treatment at the significance level of 5% are McCabe score, clinical severity of the disease, patient mobility and concurrent infections.

• Keywords: analiza ishoda liječenja; Clostridium difficile; logistička regresija; SAS
• Keywords (english): outcomes of treatment; Clostridium difficile; logistic regression; SAS
• Language: croatian
• URN:NBN: urn:nbn:hr:217:983064
• Study programme: Title: Mathematical Statistics; Study programme type: university; Study level: graduate; Academic / professional title: magistar/magistra matematike (magistar/magistra matematike)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2019-07-11 09:42:01