prikaz prve stranice dokumenta Global Repeat Map Method for Higher Order Repeat Alpha Satellites in Human and Chimpanzee Genomes (Build 37.2 Assembly)
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Scientific paper - Original scientific paper
Global Repeat Map Method for Higher Order Repeat Alpha Satellites in Human and Chimpanzee Genomes (Build 37.2 Assembly)
Croatica Chemica Acta, 85 (2012), 3; 327-351. https://doi.org/10.5562/cca1987
Glunčić, Matko; Rosandić, Marija; Jelovina, Denis; Dekanić, Krešimir; Vlahović, Ines; Paar, Vladimir

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Glunčić, M., Rosandić, M., Jelovina, D., Dekanić, K., Vlahović, I. & Paar, V. (2012). Global Repeat Map Method for Higher Order Repeat Alpha Satellites in Human and Chimpanzee Genomes (Build 37.2 Assembly). Croatica Chemica Acta, 85. (3), 327-351. doi: 10.5562/cca1987

Glunčić, Matko, et al. "Global Repeat Map Method for Higher Order Repeat Alpha Satellites in Human and Chimpanzee Genomes (Build 37.2 Assembly)." Croatica Chemica Acta, vol. 85, no. 3, 2012, pp. 327-351. https://doi.org/10.5562/cca1987

Glunčić, Matko, Marija Rosandić, Denis Jelovina, Krešimir Dekanić, Ines Vlahović and Vladimir Paar. "Global Repeat Map Method for Higher Order Repeat Alpha Satellites in Human and Chimpanzee Genomes (Build 37.2 Assembly)." Croatica Chemica Acta 85, no. 3 (2012): 327-351. https://doi.org/10.5562/cca1987

Glunčić, M., et al. (2012) 'Global Repeat Map Method for Higher Order Repeat Alpha Satellites in Human and Chimpanzee Genomes (Build 37.2 Assembly)', Croatica Chemica Acta, 85(3), pp. 327-351. doi: 10.5562/cca1987

Glunčić M, Rosandić M, Jelovina D, Dekanić K, Vlahović I, Paar V. Global Repeat Map Method for Higher Order Repeat Alpha Satellites in Human and Chimpanzee Genomes (Build 37.2 Assembly). Croatica Chemica Acta [Internet]. 2012 [cited 2024 December 24];85(3):327-351. doi: 10.5562/cca1987

M. Glunčić, M. Rosandić, D. Jelovina, K. Dekanić, I. Vlahović and V. Paar, "Global Repeat Map Method for Higher Order Repeat Alpha Satellites in Human and Chimpanzee Genomes (Build 37.2 Assembly)", Croatica Chemica Acta, vol. 85, no. 3, pp. 327-351, 2012. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:217:217820. [Accessed: 24 December 2024]

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Metadata
Title (english)Global Repeat Map Method for Higher Order Repeat Alpha Satellites in Human and Chimpanzee Genomes (Build 37.2 Assembly)
AuthorMatko Glunčić
AuthorMarija Rosandić
AuthorDenis Jelovina
AuthorKrešimir Dekanić
AuthorInes Vlahović
AuthorVladimir Paar
Author's institutionUniversity of Zagreb
Faculty of Science
(Department of Physics)
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Physics
Abstract (english)
Alpha satellites are tandemly repeated sequences found in all human centromeres. In addition to the functional and structural role within centromere they are also a suitable model for evolutionary stud-ies, because of being subject to concerted evolution. The Global Repeat Map (GRM) algorithm is a convenient computational tool to determine consensus repeat units and their exact size within a given genomic sequence, both of monomeric and higher-order (HOR) type. Using GRM, we identify in Build 37.2 assembly fifteen different alpha satellite HORs, three of them novel, not reported previously. In the next step we compute suprachromosomal family classification and CENP-B box / pJ distributions for these HORs. All human alpha satellite sequences originate from one pra-ancestral alpha satellite monomer. For the first time we perform GRM analysis and compare human and chimpanzee alpha satellite HORs for chromosomes 4 and give an evidence that the human and chimpanzee alpha satellites originate from a common ancestor that predated the human-chimpanzee separation. We also compare the codon-like trinucleotide (CLT) extensions of human and chimpanzee chromosome 4. Our results are consistent with the expectation that the alpha satellite HORs in human and chimpanzee have been created after the human-chimpanzee separation.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleCroatica Chemica Acta
Numberingvol. 85, no. 3, pp. 327-351
p-ISSN0011-1643
e-ISSN1334-417X
DOIhttps://doi.org/10.5562/cca1987
URN:NBNurn:nbn:hr:217:217820
Publication2012
ProjectNumber: 119-0982464-1253
Title (croatian): KSA kompjutorsko istraživanje repeticija višeg reda i duplikona u humanom genomu
Leader: Vladimir Paar
Jurisdiction: Croatia
Funding stream: ZP
Document URLhttps://hrcak.srce.hr/92410
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 3.0 Unported (CC BY 3.0) icon
Created on2019-11-15 18:30:20