prikaz prve stranice dokumenta Kinesin-8 Motors Improve Nuclear Centering by Promoting Microtubule Catastrophe
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Scientific paper - Original scientific paper
Kinesin-8 Motors Improve Nuclear Centering by Promoting Microtubule Catastrophe
Physical Review Letters, 114 (2015), 7; 78103. https://doi.org/10.1103/PhysRevLett.114.078103
Glunčić, Matko; Maghelli, Nicola; Krull, Alexander; Krstić, Vladimir; Ramunno-Johnson, Damien; Pavin, Nenad; Tolić, Iva M.

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Glunčić, M., Maghelli, N., Krull, A., Krstić, V., Ramunno Johnson, D., Pavin, N. & Tolić, I. M. (2015). Kinesin-8 Motors Improve Nuclear Centering by Promoting Microtubule Catastrophe. Physical Review Letters, 114. (7). doi: 10.1103/PhysRevLett.114.078103

Glunčić, Matko, et al. "Kinesin-8 Motors Improve Nuclear Centering by Promoting Microtubule Catastrophe." Physical Review Letters, vol. 114, no. 7, 2015. https://doi.org/10.1103/PhysRevLett.114.078103

Glunčić, Matko, Nicola Maghelli, Alexander Krull, Vladimir Krstić, Damien Ramunno Johnson, Nenad Pavin and Iva M. Tolić. "Kinesin-8 Motors Improve Nuclear Centering by Promoting Microtubule Catastrophe." Physical Review Letters 114, no. 7 (2015). https://doi.org/10.1103/PhysRevLett.114.078103

Glunčić, M., et al. (2015) 'Kinesin-8 Motors Improve Nuclear Centering by Promoting Microtubule Catastrophe', Physical Review Letters, 114(7). doi: 10.1103/PhysRevLett.114.078103

Glunčić M, Maghelli N, Krull A, Krstić V, Ramunno Johnson D, Pavin N, and sur.. Kinesin-8 Motors Improve Nuclear Centering by Promoting Microtubule Catastrophe. Physical Review Letters [Internet]. 2015 [cited 2024 April 19];114(7). doi: 10.1103/PhysRevLett.114.078103

M. Glunčić, et al., "Kinesin-8 Motors Improve Nuclear Centering by Promoting Microtubule Catastrophe", Physical Review Letters, vol. 114, no. 7, 2015. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:217:788975. [Accessed: 19 April 2024]

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Metadata
Title (english)Kinesin-8 Motors Improve Nuclear Centering by Promoting Microtubule Catastrophe
AuthorMatko Glunčić
AuthorNicola Maghelli
AuthorAlexander Krull
AuthorVladimir Krstić
AuthorDamien Ramunno-Johnson
AuthorNenad Pavin
AuthorIva M. Tolić
Author's institutionUniversity of Zagreb
Faculty of Science
(Department of Physics)
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Physics
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract (english)
In fission yeast, microtubules push against the cell edge, thereby positioning the nucleus in the cell center. Kinesin-8 motors regulate microtubule catastrophe; however, their role in nuclear positioning is not known. Here we develop a physical model that describes how kinesin-8 motors affect nuclear centering by promoting a microtubule catastrophe. Our model predicts the improved centering of the nucleus in the presence of motors, which we confirmed experimentally in living cells. The model also predicts a characteristic time for the recentering of a displaced nucleus, which is supported by our experiments where we displaced the nucleus using optical tweezers.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titlePhysical Review Letters
Numberingvol. 114, no. 7, 78103
p-ISSN0031-9007
e-ISSN1079-7114
DOIhttps://doi.org/10.1103/PhysRevLett.114.078103
URN:NBNurn:nbn:hr:217:788975
Publication2015
Document URLhttp://link.aps.org/doi/10.1103/PhysRevLett.114.078103
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Public noteCopyright (2015) by the American Physical Society. (Received 5 May 2014; revised manuscript received 14 December 2014; published 18 February 2015.
Created on2020-01-11 12:58:10