Doze izvan ciljnog volumena pri neuroradiokirurgiji uređajem gama nož

master's thesis

• Title (english): Doses outside the target volume in neuroradesurgery with a gamma knife device
• Author: Alen Polović
• Mentor: Marija Majer (mentor)
• Committee member: Marija Majer (predsjednik povjerenstva)
• Committee member: Ilja Gogić (član povjerenstva)
• Committee member: Tomislav Bokulić (član povjerenstva)
• Committee member: Matija Kazalicki (član povjerenstva)
• Committee member: Mihael Makek (član povjerenstva)
• Granter: University of Zagreb; Faculty of Science; (Department of Mathematics); Zagreb
• Defense date and country: 2021-09-22, Croatia
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Mathematics
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Physics

Abstract

U ovom radu izmjerene su doze izvan ciljnog volumena prilikom radioneurokirurškog zahvata uređajem Leksell Gamma Knife Icon. Korišteni su termoluminiscentni dozimetri na bazi LiF sa primjesama Mg i Ti, poznatiji kao TLD-700. Doze su mjerene u antropomorfnom fantomu koji predstavlja desetogodišnje dijete oba spola. Iako se ionizirajuće zračenje prilikom radioneurokirurškog tretmana prvobitno koristi za dobrobit pacijenta, ono može izazvati neželjene učinke u organizmu. Posebna pozornost je... More usmjerena prema dozama izvan ciljnog volumena koje apsorbiraju djeca, budući da je organizam u razvoju posebno osjetljiv na ionizirajuće zračenje. Na osnovi rezultata mjerenja apsorbiranih doza određena je srednja doza koju apsorbira štitnjača prilikom medicinskog oslikavanja pridruženim uređajem za računalnu tomografiju stožastim snopom, raspodjela doza apsorbiranih prilikom tretmana uređajem Leksell Gamma Knife Icon u ovisnosti o udaljenosti od ciljnog volumena, raspodjela doza apsorbiranih prilikom tretmana uređajem Leksell Gamma Knife Icon u organima i usporedba dobivene raspodjele doze u organima sa dozama izmjerenim prilikom ozračivanja istog ciljnog volumena koristeći uređaj Leksell Gamma Knife Model C, te radioterapijske tehnike koje koriste fotonske (IMRT) i protonske (IMPT) snopove. Doze apsorbirane prilikom tretmana uređajem Leksell Gamma Knife Icon višestruko su manje nego doze apsorbirane prilikom tretmana uređajem Leksell Gamma Knife Model C, približno su jednake dozama apsorbiranim prilikom tretmana fotonskim snopom i višestruko veće od doza apsorbiranih prilikom tretmana protonskim snopom. Less

Abstract (english)

In this work, doses outside the target volume were measured during radioneurosurgery using Leksell Gamma Knife Icon. LiF-based thermoluminescent dosimeters with Mg and Ti admixtures, better known as TLD-700, were used. Doses were measured in an anthropomorphic phantom representing a ten-year-old child of both sexes. Although ionizing radiation during radioneurosurgical treatment is originally used for benefiting the patient, it can cause side e ects in the body. Particular attention is... More paid to doses outside the target volume absorbed by children, as the developing organism is particularly sensitive to ionizing radiation. Based on measurements of absorbed doses, the mean dose absorbed by the thyroid gland during medical imaging with the Cone Beam Computed Tomography device was determined, along with the distance dependence of absorbed doses during treatment using Leksell Gamma Knife Icon, organ distribution of doses during treatment using Leksell Gamma Knife Icon and comparison of the obtained dose distribution in the organs with the doses measured when irradiating the same target volume using the Leksell Gamma Knife Model C, and radiotherapy techniques using photon (IMRT) and proton (IMPT) bundles. Doses absorbed during treatment with Leksell Gamma Knife Icon are many times smaller than doses absorbed during treatment with Leksell Gamma Knife Model C, approximately equal to doses absorbed during photon beam treatment and many times higher than doses absorbed during proton beam treatment. Less

• Keywords: radioneurokirurški zahvat; uređaj Leksell Gamma Knife Icon; radioterapijske tehnike; uređaj Leksell Gamma Knife Model C; tretman fotonskim snopom; tretman protonskim snopom
• Keywords (english): radioneurosurgery; Leksell Gamma Knife Icon; Cone Beam Computed Tomography; Leksell Gamma Knife Model C; photon beam treatment; proton beam treatment
• Language: croatian
• URN:NBN: urn:nbn:hr:217:040863
• Study programme: Title: Mathematics and Physics Education; specializations in: Mathematics and Physics Education; Course: Mathematics and Physics Education; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: magistar/magistra edukacije matematike i fizike (magistar/magistra edukacije matematike i fizike)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2021-11-05 11:20:08