3D printanje organa

undergraduate thesis

• Title (english): 3D organ printing
• Author: Tamara Vuk
• Mentor: Inga Marijanović (mentor)
• Granter: University of Zagreb; Faculty of Science; (Department of Biology); Zagreb
• Defense date and country: 2015, Croatia
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Biology

Abstract

Tkivno inženjerstvo još je uvijek daleko od zadanog cilja, izrade funkcionalnih zamjenskih humanih organa te je razumno pretpostaviti da tehnologija biofabrikacije vjerojatno neće omogućiti stvaranje 100% autentičnih funkcionalnih kopija organa. Realniji tehnološki cilj je projektiranje tkivnih i organskih konstrukata sa sposobnošću obnavljanja funkcije oštećenih organa. Zahvaljujući brzo-razvijajućem biomimetičkom pristupu koji predstavlja integraciju inženjerstva i razvojne biologije, taj je cilj postao ostvariv. Brzom napretku ovog područja osobito je pridonio početak upotrebe 3D printera u izradi bioloških struktura, odnosno bioprintanje. Ovaj rad opisuje tradicionalne pristupe tkivnog inženjerstva, ukazuje na njihove nedostatke, uspoređuje ih s novijim metodama biomimetičkog pristupa te predstavlja nedavni napredak u izradi živih struktura koji je omogućila revolucionarna tehnologija bioprintanja.

Abstract (english)

Tissue engineering is still far from the set goal, production of functional replacement human organs and it is reasonable to assume that biofabrication technology will probably not allow the creation of 100% authentic copies of functional organs. A more realistic technological goal is to design tissue and organ constructs with the ability to restore function of damaged organs. Thanks to the fast-evolving biomimetic approach which represents the integration of engineering and developmental biology, that goal has become feasible. The rapid progress in this area was especially stimulated by the beginning of use of 3D printers in the development of biological structures or bioprinting. This paper describes the traditional approaches to tissue engineering, highlights their shortcomings, compares them with newer methods of biomimetic approach and presents recent advances in the development of the living structures which were enabled by the revolutionary technology of bioprinting.

• Keywords: 3D printanje; 3D printanje organa; tkivno inženjerstvo; bioprintanje
• Keywords (english): 3D printing; 3D organ printing; tissue engineering; bioprinting
• Language: croatian
• URN:NBN: urn:nbn:hr:217:498073
• Study programme: Title: Molecular Biology; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2017-12-19 09:31:45