Sekundarni metaboliti u mesojednih biljaka iz porodice Droseraceae

undergraduate thesis

• Title (english): Secondary metabolites in carnivorous plants from the Droseraceae family
• Author: Ida Svetličić
• Mentor: Mirta Tkalec (mentor)
• Granter: University of Zagreb; Faculty of Science; (Department of Biology); Zagreb
• Defense date and country: 2013, Croatia
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Biology

Abstract

Zbog nedostataka umjetno sintetiziranih lijekova, sve se više radi na otkrivanju zdravstvenih učinka biljnih ekstrakta koji bi mogli imati važnu ulogu u borbi protiv raka i drugih bolesti. Naftokinoni i flavonoidi su najvažniji sekundarni metaboliti mesojednih biljaka iz porodice Droseraceae. Pokazalo se da imaju brojna farmakološka djelovanja među kojima je ublažavanja kašlja ali i uništavanje tumorskih stanica. Zbog sve manje površine njihovog prirodnog staništa, biljke porodice Droseraceae zakonom su zaštićene vrste u mnogo zemalja. Kako bi bila osigurana dovoljna količina biljnog materijala za ekstrakciju medicinski korisnih sekundarnih metabolita, potreban je intenzivan uzgoj ovih biljaka u kulturama in vitro. Dodatkom elicitora u medije za uzgoj postiže se vrlo visoki prinos naftokinona i flavonoida. Ključno je istražiti prave uvjete za uzgoj in vitro, kao što su koncentracija i vrsta nutrijenata i elicitora, te optimalni pH medija za pojedinu vrstu. Također treba dodatno istražiti i međudjelovanje pojedinih sekundarnih metabolita da bi se utvrdilo u kojim je uvjetima ono sinergističko, a u kojim antagonističko.

Abstract (english)

Due to the flaws of artificially synthesized drugs, more work is being done on discovering health effects of plant extracts which could play an important role in fighting cancer and other diseases. Naphtoquinons and flavonoids are the most important secondary metabolites in carnivorous plants from the family Droseraceae. It has been shown that they have numerous pharmacological effects, including mitigation of cough and destruction of tumor cells. Due to ever-smaller areas of their natural habitat, the plant family Droseraceae is legally protected species in many countries. In order to ensure a sufficient amount of plant material for medically useful secondary metabolites extraction, intensive in vitro cultivation of these plants is required. By adding elicitors to the culture medium, high income in naphtoquinon and flavonoid content is achieved. The key is to explore the right conditions to grow these plants in vitro, such as the concentration and type of nutrients and elicitors, and the optimum pH for each type of media. The interaction of certain secondary metabolites should also be further explored to find out in which conditions it is synergistic and in which antagonistic.

• Keywords: sekundarni metaboliti; mesojedne biljke
• Keywords (english): secondary metabolites; carnivorous plants
• Language: croatian
• URN:NBN: urn:nbn:hr:217:978948
• Study programme: Title: Ecology; Study programme type: university; Study level: undergraduate; Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2018-04-25 09:24:24