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MECHANISM OF CHROMOSOME ALIGNMENT BY MICROTUBULE OVERLAPDEPENDENT FORCES AND ITS RELEVANCE FOR CHROMOSOME
SEGREGATION ERRORS
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Patrik Risteski
Chromosome alignment is a hallmark of mitosis and alignment defects, which persist in
anaphase, lead to direct aneuploidy. Alignment at the spindle equator depends on pulling forces
exerted at kinetochore fiber tips together with polar ejection forces. However, kinetochore
fibers are also subjected to forces that drive their poleward flux. Here I introduce a microtubule
flux-driven centering mechanism that relies on flux generated by forces within the overlaps of
bridging and...
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MEĐUODNOS BDNF, IL-6 I POKAZATELJA OKSIDACIJSKOG STRESA PRI DEMIJELINIZACIJSKIM OŠTEĆENJIMA
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Andrijana Bogoje Raspopović
BDNF, IL-6 i biljezi oskidacijskog stresa nedvojbeno imaju utjecaj na demijelinizacijski proces umultiploj sklerozi. Točni mehanizmi utjecaja na upalnu i neurodegenerativnu fazu nisu upotpunosti razjašnjeni. U ovo istraživanje je uključeno 60 ispitanika (19 muških i 41 ženskih)koji zadovoljavaju kriterije relapsno remitentne multiple skleroze (RRMS), i 66 zdravihkontrola (24 muških, 42 ženskih). Srednja dob oboljelih i zdravih je 43,5 godina. Iz krviispitanika određena je razina...
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MICROBIAL COMMUNITIES IN OLIGOTROPHIC MARINE ECOSYSTEMS
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Katarina Kajan
Oligotrophic ecosystems are characterized by low nutrient concentration and low primary production. Climate change and anthropogenic nutrient loading affect the microbial communities of oligotrophic marine ecosystems, and therefore, understanding the essential functions of microbial communities is extremely important for understanding environmental changes. However, studying uncultured microorganisms and complex microbial communities in oligotrophic ecosystems remains a scientific challenge....
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MOLECULAR IDENTIFICATION OF FRESHWATER PATHOGENIC OOMYCETES
AND DETERMINATION OF NOVEL FACTORS THAT PROMOTE THEIR
SPREADING
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Dora Pavić
Aphanomyces astaci and Saprolegnia spp. are considered as the most destructive Oomycota
pathogens of freshwater animals, both in natural habitats and in aquaculture, and this dissertation
addressed several understudied aspects of their ecology. First, a highly sensitive S. parasiticaspecific ddPCR assay was developed, which allowed absolute quantification of the pathogen in
environmental DNA samples. Further, the results obtained provided information on the
microbiological and...
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MOLEKULARNA I BIOLOŠKA KARAKTERIZACIJA VIRUSA UVIJENOSTI LISTA VINOVE LOZE 3 IZ
AUTOHTONIH DALMATINSKIH SORTI
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Mate Čarija
Virus uvijenosti lista vinove loze 3 (grapevine leafroll-associated virus 3, GLRaV-3,
Closteroviridae) uzročnik je bolesti uvijenosti lista, jedne od ekonomski najznačajnijih viroza
vinove loze. U ovom istraživanju, u uzorcima 16 autohtonih dalmatinskih sorti i klonskih
kandidata sorte 'Plavac Mali', primjenom molekularnih metoda napravljen je pregled
pojavnosti ekonomski štetnih virusa vinove loze uz poseban osvrt na genomske varijante
GLRaV-3. Utvrđena je dominantna pojavnost...
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MOLEKULARNA KARAKTERIZACIJA PROKARIOTSKIH ZAJEDNICA U EUKSINOM OKOLIŠU ROGOZNIČKOGA JEZERA
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Milan Čanković
Primjenom sekvenciranja 16S rRNA gena Sangerovom metodom, sekvenciranjem nove generacije te
kvantitativnom lančanom reakcijom polimerazom detaljno je istražena prostorno-vremenska raspodjela,
taksonomska struktura i brojnost sulfat-reducirajućih bakterija i ukupnih prokariotskih zajednica u
kemoklini, monimolimnionu i sedimentu Rogozničkoga jezera. Raspodjela ovih zajednica usko je
povezana s fizičko-kemijskim obilježjima okoliša. Tijekom stratifikacije kemoklinom dominira
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Machine learning-based reconstruction of oceanographic patterns
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Leon Ćatipović
Software sensor augmentation utilises various machine learning algorithms to increase the range, resolution, or absolute accuracy of measurements. Within the domain of oceanographic remote sensing missing data represent a frequent issue. Although there exist numerous methods and models for estimating the missing data based on statistics, the issue remains open. Recent research have shown that a specific architecture of neural networks can be utilised to reconstruct satellite-derive sear...
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Magnetotransport properties of selected high entropy alloys
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Marko Kuveždić
This thesis presents the findings of a comprehensive, systematic study of transport properties, including resistivity, Hall effect, magnetoresistance, and superconductivity, in amorphous quinary alloys of early and late transition metals. The research focused on metallic glass ribbons from three alloy systems: (TiZrNbNi)1−xCux, (TiZrNbCu)1−xNix, and (TiZrNbCu)1−xCox, spanning a broad composition range, along with three alloy variants with a fixed TL (Cu, Ni) content and compositions:...
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Magnetska i nabojna uređenja u Kupratnim supravodičima
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Goran Nikšić
Glavna tema rada je magnetski odziv itinerantnih fermiona u nekoliko modela vodljivih ravnina u kupratnim visokotemperaturnim supravodičima. Poseban naglasak stavljamo na razlike u spektrima ispod i iznad temperature otvaranja pseudoprocjepa. Na početku predstavljamo kuprate i njihov poprilično složen fazni dijagram. U fazi sa pseudoprocjepom, koja se javlja ispod karakteristične temperature T*, samo dio Fermijeve plohe je u procjepu, a u njoj se pronalazi i mnoštvo različitih...
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