Ispitivanje vezanja glukozamina za zlatne nanočestice Ramanovom spektroskopijom

master's thesis

• Title (english): Glucosamine to gold nanoparticles binding studied using Raman spectroscopy
• Author: Sandro Brljafa
• Mentor: Vlasta Mohaček Grošev (mentor)
• Mentor: Vedran Đerek (komentor)
• Committee member: Vedran Đerek (predsjednik povjerenstva)
• Committee member: Vlasta Mohaček Grošev (član povjerenstva)
• Committee member: Maja Planinić (član povjerenstva)
• Committee member: Mario Basletić (član povjerenstva)
• Committee member: Katarina Jeličić (član povjerenstva)
• Granter: University of Zagreb; Faculty of Science; (Department of Physics); Zagreb
• Defense date and country: 2021-02-26, Croatia
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Physics

Abstract

Vezanje molekula bilo za podloge koje sadrže nanočestično zlato, bilo za nanočestice zlata, primjenjuje se u forenzici, medicini, biologiji, arheologiji te u mnogim drugim područjima gdje se SERS (surface-enhanced Raman spectroscopy) koristi. U ovom diplomskom radu eksperimentalno se ispituje postoji li vezanje molekule glukozamina, molekule glukoze s NH_2 skupinom, za nanočestice zlata u vodenoj otopini. Ovaj modelni sistem služi za provjeru detekcije većih molekula poput hijaluronske kiseline te aminokiselina u vrlo malim količinama.

Abstract (english)

Binding of molecules to substrates containing nanoparticle gold is used in forensics, medicine, biology, archeology and in many other fields where SERS (surfaceenhanced Raman spectroscopy) is used. In this graduate thesis, it is experimentally investigated and studied whether there is a binding of a glucosamine molecule (a glucose molecule with the NH_2 functional group) to gold nanoparticles in water solution. This model system serves to check the possibility of detection of larger molecules such as hyaluronic and amino acids acid and serves to improve the detection of substances present in as small quantities as possible.

• Keywords: Raman; spektroskopija; vibracijski spektar; spektar; molekula
• Keywords (english): Raman; spectroscopy; vibrational spectrum; spectrum; molecule
• Language: croatian
• URN:NBN: urn:nbn:hr:217:646910
• Study programme: Title: Physics; specializations in: Education; Course: Education; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: magistar/magistra edukacije fizike (magistar/magistra edukacije fizike)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2021-04-27 12:36:12